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ORIGINAL RESEARCH article
Front. Endocrinol.
Sec. Thyroid Endocrinology
Volume 16 - 2025 | doi: 10.3389/fendo.2025.1445977
Hypothyroidism monitoring and control during the first trimester of pregnancy in Catalonia
Provisionally accepted
Glòria Tena Vivó 1*
Oriol Cunillera Puértolas 2*
Mercè Albareda Riera 3 Neus Parellada Esquius 1 Mònica Isidro Albaladejo 1 Gemma Rodríguez Palomar 1 Silvia Palmero Aliste 1 Lluís Vila Vila 3- 1 Catalan Health Institute (ICS), Barcelona, Catalonia, Spain
- 2 Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Cornellà de Llobregat, Spain
- 3 Hospital of Sant Joan Despí Moisès Broggi, Sant Joan Despi, Spain
Objective: This study aims to describe hypothyroidism monitoring and control during the first trimester of pregnancy in women with known hypothyroidism in Catalonia Material and methods: Pregnancies registered in primary care in Catalonia between 2014 and 2016 were retrospectively studied. Women with hypothyroidism were selected for the study.Hypothyroidism was defined if on the date of the last menstrual period (LMP), there was an updated thyroid hormone prescription (code ATC H03AAlevothyroxine) or any of the following active diagnostic codes: ICD-10: E02, E03, E89.0.To evaluate hypothyroidism monitoring and control, Thyrotropin (TSH) tests during the first trimester of pregnancy were considered and categorised according to the reference values of each laboratory.Out of 111811 pregnancies, 5574 had known hypothyroidism. TSH was evaluated in 3158 (56.65%) of them. TSH values were within the recommended ranges in 1146 (36.3%)of the cases, being low abnormal in 53 of them (1.7%) and high abnormal in 1959 (62%).TSH testing was not evaluated in almost half of the pregnant women with known hypothyroidism in primary care services in Catalonia during the pregnancy first trimester. Among those tested, more than two thirds had TSH levels outside the target range. This means that it is essential to improve the management of hypothyroidism during the first trimester of pregnancy in Catalonia.
Keywords: Hypothyroidism, Pregnancy, Prevalence, Hypothyroidism monitoring and Hypothyroidism control, Hypothyroidism monitoring, Hypothyroidism control
Received: 08 Jun 2024; Accepted: 17 Feb 2025.
Copyright: © 2025 Tena Vivó, Cunillera Puértolas, Albareda Riera, Parellada Esquius, Isidro Albaladejo, Rodríguez Palomar, Palmero Aliste and Vila. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Glòria Tena Vivó, Catalan Health Institute (ICS), Barcelona, 08007, Catalonia, Spain
Oriol Cunillera Puértolas, Fundació Institut Universitari per a la recerca a l'Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Cornellà de Llobregat, Spain
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