Friederike Behler-Janbeck ¹ Anke Baranowsky ² Timur Yorgan ³ Michelle Y. Jaeckstein ¹ Anna Worthmann ¹ Marceline M. Fuh ¹ Karthikeyan Gunasekaran ¹ Gisa Tiegs ⁴ Michael Amling ³ Thorsten Schinke ³ Joerg Heeren ^1*

• ¹ Department of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany
• ² Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany
• ³ Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany
• ⁴ Institute for Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, Hamburg, Hamburg, Germany

• please read through all the templates before choosing • pick the most relevant text template(s) from the following page and delete all others.• edit the text as necessary, ensuring that the original incorrect text is included for the record, please see the below. • please do not use any extra formatting when editing the templates, and only modify the red text unless absolutely necessary • submit to Frontiers following the instructions on this page.When the original text contained incorrect information, to preserve the scientific record, please include that text when editing the below templates. For example:There was a mistake in the Funding statement, an incorrect number was used. The correct number is "2015C03Bd051.". The publisher apologizes for this mistake.The original version of this article has been updated. In the published article, there was an error in Figure 5 as published. We have realized that the wrong image in Figure 5G was unintentionally inserted due to a copy and paste error when compiling the revised version of the manuscript. The corrected Figure 5 and its caption appear below.