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REVIEW article

Front. Endocrinol.
Sec. Cellular Endocrinology
Volume 15 - 2024 | doi: 10.3389/fendo.2024.1521281

Extracellular vesicles: mechanisms and prospects in type 2 diabetes and its complications

Provisionally accepted
Liu Zi Jian Liu Zi Jian 1RuiYang Yin RuiYang Yin 2Jiaxing Tian Jiaxing Tian 2*
  • 1 Beijing University of Chinese Medicine, Beijing, China
  • 2 China Academy of Chinese Medical Sciences, Beijing, Beijing Municipality, China

The final, formatted version of the article will be published soon.

    Extracellular vesicles (EVs) are small vesicles released by cells into the surrounding environment, carrying biomolecules such as proteins, miRNA, etc., involved in intercellular communication and regulation of biological processes. With the continuous increase in the prevalence of diabetes, research on the relationship between extracellular vesicles and diabetes has attracted widespread attention. In this article, we specifically focus on the metabolic abnormalities related to EVs and diabetes, including obesity, inflammation, insulin resistance, β-cell damage, etc. We aim to explore how extracellular vesicles participate in the occurrence and development of diabetic complications, comprehensively examining the interactions between extracellular vesicles and key aspects of diabetes, forming a comprehensive and profound research framework. This is expected to provide important clues and insights for deepening our understanding of the pathophysiological mechanisms of diabetes.

    Keywords: extracellular vesicles, diabetes, Treatment, diabetic complications, mechanisms

    Received: 01 Nov 2024; Accepted: 02 Dec 2024.

    Copyright: © 2024 Zi Jian, Yin and Tian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Jiaxing Tian, China Academy of Chinese Medical Sciences, Beijing, 100700, Beijing Municipality, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.