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ORIGINAL RESEARCH article

Front. Endocrinol.
Sec. Thyroid Endocrinology
Volume 15 - 2024 | doi: 10.3389/fendo.2024.1514451
This article is part of the Research Topic Current Perspectives in the Diagnosis of Parathyroid Disease - Volume II View all articles

The Development of Patient-Specific 3D Anatomical Models in Minimally Invasive Parathyroidectomy

Provisionally accepted
Zahra Haq Zahra Haq Ahmed Ahmed Ahmed Ahmed Alaa Abdel-Salam Alaa Abdel-Salam Soudeh Chegini Soudeh Chegini Tom kurzawinsk Tom kurzawinsk Simon Morley Simon Morley Mark Mcgurk Mark Mcgurk Tarek Abdel-Aziz Tarek Abdel-Aziz *
  • University College London, London, United Kingdom

The final, formatted version of the article will be published soon.

    Background Surgery is the preferred treatment for primary hyperparathyroidism. Minimally invasive parathyroidectomy is only feasible with accurate preoperative localisation. Virtual 3D anatomical models can be constructed from patient-specific CT scans using segmentation software. Methods We aimed to create virtual 3D models from 4D-CT scans of parathyroid tumours using segmentation technology. We designed a small pilot study to assess the utility of 3D models within surgical practice. We assessed surgeon, trainee and patients’ opinion and satisfaction with the models. The NASA TLX survey was the primary data collection tool Results Creation of novel 3D models was achieved, these featured a 360-degree axis of rotation and transparency mode to assist in surgical planning. Models were used intraoperatively with the HoloLens 2 headset to locate parathyroid tumours real time before surgery. Total mean workloads for surgery planning when averaged revealed a decrease workload (39.45 vs 27.45) points with adjunctive use of models (p=0.002). Mental demand showed the greatest decrease in mean workload out of all the 6 subscales tested for in the NASA TLX (210.3 vs 136.7) points. Patient satisfaction score was statistically significant for the difference before and after seeing the 3D model regarding anatomical location (p=≤0.001), Conclusion In this work, we developed patient-specific virtual 3D anatomical models of parathyroid tumours for use in surgery using novel techniques, previously never applied to parathyroidectomy. Our initial success in model construction and subsequent opinion of surgeons, trainees and patients contributes to the developing body of literature in favour of virtual modelling for parathyroidectomy.

    Keywords: Primary hyper parathyroidism, Parathyroid - adenoma, Parathyrodectomy, minimally invasive surgery, HoloLens 2, Three dimensional mode

    Received: 20 Oct 2024; Accepted: 22 Nov 2024.

    Copyright: © 2024 Haq, Ahmed, Abdel-Salam, Chegini, kurzawinsk, Morley, Mcgurk and Abdel-Aziz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Tarek Abdel-Aziz, University College London, London, United Kingdom

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.