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ORIGINAL RESEARCH article

Front. Endocrinol.
Sec. Thyroid Endocrinology
Volume 15 - 2024 | doi: 10.3389/fendo.2024.1487490

Comparison between thyroid stimulating immunoglobulin and TSH-receptor antibodies in the diagnosis and management of Graves' disease

Provisionally accepted
Peiwei Yao Peiwei Yao *Yunliang Xie Yunliang Xie *Yunlin Wang Yunlin Wang *Chunyan Liang Chunyan Liang *Bingwen Huang Bingwen Huang *
  • Foshan Second People's Hospital, Foshan, China

The final, formatted version of the article will be published soon.

    TSH-receptor antibodies (TRAb) directed against the TSH receptor (TSH-R) induce hyperthyroidism in patients with Graves′ disease (GD). TRAb detected by previous radioimmunoassay only reflects the presence of autoantibodies, but not the function of such antibodies. Thyroid stimulating immunoglobulins (TSI) is a relatively new method for assessing TSH-receptor antibodies function. The aim of this study was to investigate the role of TSI in the diagnosis and management of GD.

    Keywords: TRAb thyroid antibodies, Thyroid-stimulating immunoglobulin, Graves' disease, Anti-hyperthyroidism drug therapy, duration of treatment

    Received: 28 Aug 2024; Accepted: 12 Nov 2024.

    Copyright: © 2024 Yao, Xie, Wang, Liang and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Peiwei Yao, Foshan Second People's Hospital, Foshan, China
    Yunliang Xie, Foshan Second People's Hospital, Foshan, China
    Yunlin Wang, Foshan Second People's Hospital, Foshan, China
    Chunyan Liang, Foshan Second People's Hospital, Foshan, China
    Bingwen Huang, Foshan Second People's Hospital, Foshan, China

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