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ORIGINAL RESEARCH article

Front. Endocrinol.
Sec. Clinical Diabetes
Volume 15 - 2024 | doi: 10.3389/fendo.2024.1484197

Factors Related to Type 2 Diabetic Retinopathy and Their Clinical Application Value

Provisionally accepted
Xuenan Lian Xuenan Lian Mingming Zhu Mingming Zhu *
  • HanDan Central Hospital, Handan, Hebei Province, China

The final, formatted version of the article will be published soon.

    To compare the differences in clinical-related factors between patients with type 2 diabetes (T2DM) and those without diabetic retinopathy (DR) and to explore the risk factors or protective factors affecting DR in T2DM patients. We performed a retrospective analysis of 380 patients with type 2 diabetes admitted to Handan Central Hospital from June 2023 to May 2024. Clinical data collected included baseline characteristics, hematological tests, metabolic indicators, and information on diabetic complications and comorbidities. Our findings identified intervention, neck vascular disease, bilateral lower limb venous thrombosis, high creatinine, high glomerular filtration rate, high chloride, high fasting C-peptide, and high lactate dehydrogenase as risk factors for DR. In contrast, High 2hour postprandial C-peptide is a protective factor for diabetic retinopathy. A logistic regression model was constructed using stepwise regression to predict DR occurrence, achieving an accuracy of 0.80 and an AUC of 0.83.

    Keywords: Type 2 diabetes1, diabetic retinopathy2, lactate dehydrogenase3, Risk Factors4, Protective factors5, logistic regression6

    Received: 21 Aug 2024; Accepted: 05 Nov 2024.

    Copyright: © 2024 Lian and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Mingming Zhu, HanDan Central Hospital, Handan, Hebei Province, China

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