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REVIEW article

Front. Endocrinol.
Sec. Diabetes: Molecular Mechanisms
Volume 15 - 2024 | doi: 10.3389/fendo.2024.1474232
This article is part of the Research Topic Exploring the Complex Interplay between Obesity, Mitochondria and Metabolic Health View all 5 articles

Mapping the Mitochondrial Landscape in T2DM: Key Findings from 2003-2023

Provisionally accepted
怡 谭 怡 谭 1Mingjun Liu Mingjun Liu 1*Xinfeng Zhou Xinfeng Zhou 1Tianjiao Gao Tianjiao Gao 2*Jinxu Fang Jinxu Fang 1*Sixian Wang Sixian Wang 1*Shaotao Chen Shaotao Chen 1*
  • 1 Changchun University of Chinese Medicine, Changchun, China
  • 2 The Affiliated Hospital of Changchun University of Traditional Chinese Medicine, Changchun, Jilin Province, China

The final, formatted version of the article will be published soon.

    Backgound: T2DM, a chronic metabolic disorder, poses a significant threat to global public health. Mitochondria play a crucial role in the pathogenesis of T2DM. This study intends to investigate the correlation between mitochondria and T2DM over the past two decades (2003-2023) through bibliometric analysis. Its objectives are to pinpoint trends, emphasize research priorities, and establish a foundation for future investigations. Methods: A literature search was conducted using the SCI-E database. All recorded results were downloaded in plain text format for further analysis. The following terms were analyzed using Vosviewer 1.6.18, citespace 6.3r1, bibliometrix in RStudio (v.4.4.1), and Microsoft Excel 2021: country, institution, author, journal, references, and keywords. Results: From January 1, 2003 to December 31, 2023, a total of 2,732 articles were retrieved. The United States, China, and Italy contributed most of the records.UNIVERSITY OF CALIFORNIA SYSTEM, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL INSERM, and US DEPARTMENT OF VETERANS AFFAIRS were the top 3 most productive institutions. rocha milagros, victor victor m had the most publications, followed by roden michael, and petersen kf had the most citations together. DIABETES published the most articles on research on this topic, followed by AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM,DIABETOLOGIA. The key points of this topic are the relationship between mitochondria and T2DM, the skeletal muscle mitochondrial changes observed in T2DM, and the impact of mitochondrial dysfunction on T2DM. Over the past five years, particle dynamics, mitochondrial dysfunction, and mechanism research have emerged as significant focal points in this field. Conclude:This paper successfully identified the key areas and emerging trends in the relationship between mitochondria and T2DM, thereby offering valuable insights for future research.

    Keywords: Mitochondria, T2DM, bibliometric analysis, VOSviewer, Citespace

    Received: 01 Aug 2024; Accepted: 01 Nov 2024.

    Copyright: © 2024 谭, Liu, Zhou, Gao, Fang, Wang and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Mingjun Liu, Changchun University of Chinese Medicine, Changchun, China
    Tianjiao Gao, The Affiliated Hospital of Changchun University of Traditional Chinese Medicine, Changchun, 130021, Jilin Province, China
    Jinxu Fang, Changchun University of Chinese Medicine, Changchun, China
    Sixian Wang, Changchun University of Chinese Medicine, Changchun, China
    Shaotao Chen, Changchun University of Chinese Medicine, Changchun, China

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