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REVIEW article
Front. Endocrinol.
Sec. Reproduction
Volume 15 - 2024 |
doi: 10.3389/fendo.2024.1399757
This article is part of the Research Topic Environmental Threats to Human Reproduction View all 12 articles
The Role of Epigenetics in Women's Reproductive Health: The Impact of Environmental Factors
Provisionally accepted- 1 School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
- 2 Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
This paper explores the significant role of epigenetics in women's reproductive health, focusing on the impact of environmental factors. It highlights the crucial link between epigenetic modificationssuch as DNA methylation and histones post-translational modificationsand reproductive health issues, including infertility and pregnancy complications. The paper reviews the influence of pollutants like PM2.5, heavy metals, and endocrine disruptors on gene expression through epigenetic mechanisms, emphasizing the need for understanding how dietary, lifestyle choices, and exposure to chemicals affect gene expression and reproductive health. Future research directions include deeper investigation into epigenetics in female reproductive health and leveraging gene editing to mitigate epigenetic changes for improving IVF success rates and managing reproductive disorders.
Keywords: epigenetics, Women, reproductive, environmental factors, Reproductive Health
Received: 12 Mar 2024; Accepted: 28 Aug 2024.
Copyright: © 2024 Yu, Xu, Song, Zhu, Liu, Liu and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Yingjie Ma, Shandong University of Traditional Chinese Medicine, Jinan, 250355, Shandong Province, China
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