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REVIEW article

Front. Endocrinol.
Sec. Reproduction
Volume 15 - 2024 | doi: 10.3389/fendo.2024.1399757
This article is part of the Research Topic Environmental Threats to Human Reproduction View all 12 articles

The Role of Epigenetics in Women's Reproductive Health: The Impact of Environmental Factors

Provisionally accepted
Xinru Yu Xinru Yu 1Jiawei Xu Jiawei Xu 2Bihan Song Bihan Song 2Runhe Zhu Runhe Zhu 2Jiaxin Liu Jiaxin Liu 2Yifan Liu Yifan Liu 2Yingjie Ma Yingjie Ma 2*
  • 1 School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China
  • 2 Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China

The final, formatted version of the article will be published soon.

    This paper explores the significant role of epigenetics in women's reproductive health, focusing on the impact of environmental factors. It highlights the crucial link between epigenetic modificationssuch as DNA methylation and histones post-translational modificationsand reproductive health issues, including infertility and pregnancy complications. The paper reviews the influence of pollutants like PM2.5, heavy metals, and endocrine disruptors on gene expression through epigenetic mechanisms, emphasizing the need for understanding how dietary, lifestyle choices, and exposure to chemicals affect gene expression and reproductive health. Future research directions include deeper investigation into epigenetics in female reproductive health and leveraging gene editing to mitigate epigenetic changes for improving IVF success rates and managing reproductive disorders.

    Keywords: epigenetics, Women, reproductive, environmental factors, Reproductive Health

    Received: 12 Mar 2024; Accepted: 28 Aug 2024.

    Copyright: © 2024 Yu, Xu, Song, Zhu, Liu, Liu and Ma. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Yingjie Ma, Shandong University of Traditional Chinese Medicine, Jinan, 250355, Shandong Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.