AUTHOR=Muhamad Jamil Nur Khadijah , Mohamed Isa Naina , Mokhtar Sabarul Afian , Leong Juzaily Fekry , Kamudin Nur Azree Ferdaus , Muhammad Norliza TITLE=Development of self-administered questionnaire on barriers, prescription practices, and guideline adherence of osteoporosis management among tertiary care clinicians: content validity and reliability analysis JOURNAL=Frontiers in Endocrinology VOLUME=15 YEAR=2024 URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1393500 DOI=10.3389/fendo.2024.1393500 ISSN=1664-2392 ABSTRACT=Objective

This study outlined the development of the barriers, prescribing practices, and guideline adherence for osteoporosis management according to the Clinicians’ Osteoporosis Questionnaire (COQ) followed by an assessment of the content validity index and reliability test.

Methods

The development of the COQ was performed in two stages. Stage I involved the development of the COQ, and stage II involved judgmental evidence and quantification of the questionnaire. Five panel experts related to the study area and five clinicians participated in the validity of the COQ assessment. Fifty clinicians took part in the reliability test evaluation by filling out the questionnaire twice at 2-week intervals. The content validity index (CVI) and content validity ratio (CVR) were analyzed using Microsoft Excel, while Cohen’s kappa statistic was used to determine the test–retest reliability using SPSS version 29.

Results

Forty items and three domains, namely, barriers, prescribing practices, and guideline adherence for osteoporosis management, were identified in the COQ (version 4.0). The scale-level CVI (S-CVI/Ave) for every domain was above 0.9, which is considered acceptable. The CVRs for all the items were above 0.7, except for two items in the barrier domain and two items in the guideline adherence domain. Two items were revised to improve the clarity of the item, and other items were retained based on consensus among the expert panel. Between the test and retest, the reliability of individual items ranged from moderate to almost perfect for the barrier domain (k = 0.42–0.86), prescribing practice domain (k = 0.79–0.87), and guideline adherence domain (k = 0.46–1). None of the items had “fair” or “poor” agreement. Thus, the 40-item COQ (version 4.0) was finalized following the content and face validity analysis.

Conclusions

Through an iterative process, the development and assessment of the COQ showed a high degree of content validity and reliability in measuring the barriers, prescribing practices, and guideline adherence among clinicians managing osteoporosis. Future studies should aim to further validate this instrument across different populations and settings, as well as explore methods to enhance its reliability and validity.