AUTHOR=Ge Shenghui , Zhang Hui , Wang Jun , Li Huiqin , Su Xiaofei , Ding Dafa , Ma Jianhua 

TITLE=Accuracy of a novel real-time continuous glucose monitoring system: a prospective self-controlled study in thirty hospitalized patients with type 2 diabetes

JOURNAL=Frontiers in Endocrinology

VOLUME=15

YEAR=2024

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1374496

DOI=10.3389/fendo.2024.1374496

ISSN=1664-2392

ABSTRACT=<sec><title>Aims</title><p>The present study aimed to investigate the accuracy of the Glunovo<sup>®</sup> real-time continuous glucose monitoring system (rtCGMS).</p></sec><sec><title>Methods</title><p>We conducted a 14-day interstitial glucose level monitoring using Glunovo<sup>®</sup> rtCGMS on thirty hospitalized patients with type 2 diabetes. The flash glucose monitoring (FGM) was used as a self-control. Consistency tests, error grid analysis, and calculation of the mean absolute relative difference (MARD) were performed using R software to assess the accuracy of Glunovo<sup>®</sup> rtCGMS.</p></sec><sec><title>Results</title><p>Glunovo<sup>®</sup> exhibited an overall MARD value of 8.89% during hospitalization, compared to 10.42% for FGM. The overall percentages of glucose values within ±10%/10, ± 15%/15, ± 20%/20, ± 30%/30, and ±40%/40 of the venous blood glucose reference value were 63.34%, 81.31%, 90.50%, 97.29%, and 99.36% for Glunovo<sup>®</sup>, respectively, compared with 61.58%, 79.63%, 88.31%, 96.22% and 99.23% for FGM. The Clarke Error Grid Analysis showed that 99.61% of Glunovo<sup>®</sup> glucose pairs and 100.00% of FGM glucose pairs within zones A and B.</p></sec><sec><title>Conclusion</title><p>Our study confirms the superior accuracy of Glunovo<sup>®</sup> in monitoring blood glucose levels among hospitalized patients with type 2 diabetes.</p></sec>