AUTHOR=Feng Jingwen , Zhang Qiuhua , Chen Baoyi , Chen Jinping , Wang Wenjun , Hu Yuhang , Yu Jiabin , Huang Huiming 

TITLE=Effects of high-intensity intermittent exercise on glucose and lipid metabolism in type 2 diabetes patients: a systematic review and meta-analysis

JOURNAL=Frontiers in Endocrinology

VOLUME=15

YEAR=2024

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1360998

DOI=10.3389/fendo.2024.1360998

ISSN=1664-2392

ABSTRACT=<sec><title>Objective</title><p>To evaluate the effects of high-intensity interval training (HIIT) on glycolipid metabolism among type 2 diabetes patients.</p></sec><sec><title>Methods</title><p>HIIT is consistent with an exercise program (65%-90%VO<sub>2</sub>max or 75%-95% HRmax; exercise cycle≥2 weeks; frequency ≥ 2 times/week). A meta-analysis was conducted utilizing the random effects model to synthesize the data.</p></sec><sec><title>Results</title><p>A total of 22 RCT studies with 1034 diabetic patients were included. Compared to moderate-intensity aerobic exercise or conventional controls, HIIT yields noteworthy effects on FBG (MD: -0.55; 95% CI: -0.85- -0.25, Hedges’ g =0.98), 2h-PG (MD: -0.36; 95% CI: -0.57- -0.14, Hedges’ g =1.05), FINS (MD: -0.41; 95% CI: -0.79- -0.03, Hedges’ g =1.07), HbA1c (MD: -0.60; 95% CI: -0.84- -0.36, Hedges’ g =2.69), TC (MD: -0.58; 95% CI: -0.80- -0.36, Hedges’ g =2.36), TG (MD: -0.50; 95% CI: -0.86- -0.14, Hedges’ g =1.50), HDL (MD: 0.62; 95% CI: 0.29–0.95, Hedges’ g =1.19) and LDL (MD: -0.31; 95% CI: -0.56- -0.08, Hedges’ g =0.91), all of the above p&lt;0.01.</p></sec><sec><title>Conclusions</title><p>HIIT has been shown to improve glucose and lipid metabolism in patients with type 2 diabetes, especially in HbA1c, TC, TG, and HDL. For patients between the ages of 40 and 60 with less than 5 years of disease, exercise programs of moderate to longer duration or moderate to high intensity will produce more favorable results.</p></sec>