AUTHOR=Mei Youwen , Wang Yacong , Ke Xue , Liang Xuefei , Lin Yonghong , Wang Fang 

TITLE=Does endometrial receptivity array improve reproductive outcomes in euploid embryo transfer cycles? a systematic review

JOURNAL=Frontiers in Endocrinology

VOLUME=14

YEAR=2023

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1251699

DOI=10.3389/fendo.2023.1251699

ISSN=1664-2392

ABSTRACT=<p>Besides chromosomal normality, endometrial receptivity is an important factor in determining successful pregnancies. Endometrial receptivity array (ERA), a promising endometrial receptivity test, was speculated to improve the reproductive outcomes. However, its effectiveness is controversial in clinical practice. Therefore, we conducted this review to investigate its role in <italic>in vitro</italic> fertilization (IVF) treatment. To eliminate the interference of embryo quality, we only analyzed studies that originally reported the reproductive outcomes of patients who underwent ERA-guided euploid embryo transfer (EET). Unexpectedly, it revealed that ERA could not optimize the reproductive outcomes in EET cycles, no matter in general infertile population or in patients with a history of previous failed embryo transfers.</p>