AUTHOR=Zhou Guanqing , Zhang Mimi , Zhang Jingzhi , Feng Yaofeng , Xie Zhishen , Liu Siyi , Zhu Detu , Luo Yumei 

TITLE=The gene regulatory role of non-coding RNAs in non-obstructive azoospermia

JOURNAL=Frontiers in Endocrinology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.959487

DOI=10.3389/fendo.2022.959487

ISSN=1664-2392

ABSTRACT=<p>Non-coding RNAs are classified as small non-coding RNAs, long non-coding RNAs and circular RNAs, which are involved in a variety of biological processes, including cell differentiation, proliferation, apoptosis and pathological conditions of various diseases. Many studies have shown that non-coding RNAs are related to spermatogenesis, maturation, apoptosis, function, etc. In addition, the expression of non-coding RNAs in testicular tissue and semen of patients with non-obstructive azoospermia was different. However, the role of non-coding RNAs in the pathogenesis of non-obstructive azoospermia has not been fully elucidated, and the role of non-coding RNAs in non-obstructive azoospermia is rarely reviewed. Here we summarize the research progress of non-coding RNAs in the pathogenesis of non-obstructive azoospermia.</p>