AUTHOR=Wu Wenqi , Gong Tong , Niu Jinliang , Li Wenjin , Li Jianting , Song Xiaoli , Cui Sha , Bian Wenjin , Wang Jun TITLE=Study of bone marrow microstructure in healthy young adults using intravoxel incoherent motion diffusion-weighted MRI JOURNAL=Frontiers in Endocrinology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.958151 DOI=10.3389/fendo.2022.958151 ISSN=1664-2392 ABSTRACT=
Bone marrow is one of the most important organs in the human body. The evaluation of bone marrow microstructure and gender-related cellular and capillary networks in healthy young adults can help to better understand the process of bone metabolism. Intravoxel incoherent motion (IVIM) provides both diffusion and perfusion quantifications without requiring intravenous contrast agent injection. In this prospective study, 60 healthy young age-matched volunteers (30 men and 30 women) underwent MRI scans at 1.5 T using multi–b-value diffusion-weighted imaging on sagittal planes covering the lumbar bone marrow. The apparent diffusion coefficient (ADC), true ADC (