AUTHOR=Chang Johnny Yau-Cheung , Woo Chariene Shao-Lin , Lui David Tak-Wai , Fung Matrix Man-Him , Lee Alan Chun-Hong , Leung Eunice Ka-Hong , Woo Yu-Cho , Chow Wing-Sun , Lam Karen Siu-Ling , Tan Kathryn Choon-Beng , Lee Chi-Ho 

TITLE=Case Report: Insulinoma Co-Existing With Type 2 Diabetes – Advantages and Challenges of Treatment With Endoscopic Ultrasound-Guided Radiofrequency Ablation

JOURNAL=Frontiers in Endocrinology

VOLUME=13

YEAR=2022

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.957369

DOI=10.3389/fendo.2022.957369

ISSN=1664-2392

ABSTRACT=<p>The coexistence of insulinoma and type 2 diabetes is rare and the diagnostic process is often challenging. Continuous glucose monitoring system devices, which are more readily available nowadays, provide a useful tool for the diagnosis and evaluation of treatment response. Curative surgery is often the mainstay of treatment for insulinoma. Here, we report a Chinese patient with insulinoma diagnosed simultaneously with type 2 diabetes. His insulinoma was managed with endoscopic ultrasound guided-radiofrequency ablation (EUS-RFA) and the patient achieved complete resolution of hypoglycaemic episodes. The case illustrates that while EUS-RFA is an emerging non-invasive treatment modality for pancreatic lesions, limitations exist especially when histological confirmation is essential.</p>