AUTHOR=Bukhari Ihtisham , Zhang Yuanwei , Thorne Rick Francis , Mi Yang TITLE=Editorial: Complexity of tumor microenvironment: A major culprit in cancer development JOURNAL=Frontiers in Endocrinology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.1059885 DOI=10.3389/fendo.2022.1059885 ISSN=1664-2392