AUTHOR=Wang Ruoyu , Zuo Guangxi , Li Kunke , Li Wangting , Xuan Zhiqiang , Han Yongzhao , Yang Weihua TITLE=Systematic bibliometric and visualized analysis of research hotspots and trends on the application of artificial intelligence in diabetic retinopathy JOURNAL=Frontiers in Endocrinology VOLUME=13 YEAR=2022 URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.1036426 DOI=10.3389/fendo.2022.1036426 ISSN=1664-2392 ABSTRACT=Background

Artificial intelligence (AI), which has been used to diagnose diabetic retinopathy (DR), may impact future medical and ophthalmic practices. Therefore, this study explored AI’s general applications and research frontiers in the detection and gradation of DR.

Methods

Citation data were obtained from the Web of Science Core Collection database (WoSCC) to assess the application of AI in diagnosing DR in the literature published from January 1, 2012, to June 30, 2022. These data were processed by CiteSpace 6.1.R3 software.

Results

Overall, 858 publications from 77 countries and regions were examined, with the United States considered the leading country in this domain. The largest cluster labeled “automated detection” was employed in the generating stage from 2007 to 2014. The burst keywords from 2020 to 2022 were artificial intelligence and transfer learning.

Conclusion

Initial research focused on the study of intelligent algorithms used to localize or recognize lesions on fundus images to assist in diagnosing DR. Presently, the focus of research has changed from upgrading the accuracy and efficiency of DR lesion detection and classification to research on DR diagnostic systems. However, further studies on DR and computer engineering are required.