AUTHOR=Baulieu Etienne-Emile 

TITLE=Steroids and Brain, a Rising Bio-Medical Domain: a Perspective

JOURNAL=Frontiers in Endocrinology

VOLUME=9

YEAR=2018

URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2018.00316

DOI=10.3389/fendo.2018.00316

ISSN=1664-2392

ABSTRACT=<p>Some newly described steroid-related compounds, also found in the rest of the body, are formed and active in the central nervous system, particularly in the brain. Some are of pharmacological and physiopathological interest. We specifically report on two compounds, “MAP4343,” a new neurosteroid very efficient antidepressant, and “FKBP52,” a protein component of hetero-oligomeric steroid receptors that we found involved in cerebral function, including in Alzheimer’s disease.</p>