AUTHOR=Tannus Lucianne Righeti Monteiro , Drummond Karla Rezende Guerra , Clemente Eliete Leão da Silva , da Matta Maria de Fátima Bevilacqua , Gomes Marilia Brito , on behalf of the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG) TITLE=Predictors of Cardiovascular Autonomic Neuropathy in Patients with Type 1 Diabetes JOURNAL=Frontiers in Endocrinology VOLUME=5 YEAR=2014 URL=https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2014.00191 DOI=10.3389/fendo.2014.00191 ISSN=1664-2392 ABSTRACT=
Cardiovascular disease (CVD) is the leading cause of mortality in patients with type 1 diabetes (T1D). The cardiovascular autonomic neuropathy (CAN), although considered as an independent risk factor for CVD, remains underdiagnosed. The aim of this paper was to determine the prevalence, predictors of CAN in patients with T1D and its association with other chronic complications of diabetes. Patients with T1D underwent a clinical-epidemiological survey, had blood and urinary samples collected, performed ophthalmoscopic and clinical neurological examination and cardiovascular reflex tests. One hundred and fifty one patients with T1D, 53.6% female, 45.7% Caucasian, mean age of 33.4 ± 13 years, diabetes duration of 16.3 ± 9.5 years, and glycated hemoglobin levels of 9.1 ± 2% were evaluated. The prevalence of CAN in the studied population was 30.5%. CAN was associated with age (