AUTHOR=Yuste Mariana , PiƱeyro-Nelson Alma , Azpeitia Eugenio TITLE=A gene regulatory network model that recovers the abaxial-adaxial polarity in Arabidopsis thaliana leaf primordium JOURNAL=Frontiers in Ecology and Evolution VOLUME=12 YEAR=2024 URL=https://www.frontiersin.org/journals/ecology-and-evolution/articles/10.3389/fevo.2024.1330827 DOI=10.3389/fevo.2024.1330827 ISSN=2296-701X ABSTRACT=
Megaphylls, present in the majority of vascular plants, show in many plant lineages an abaxial-adaxial polarity in their dorsoventral axis. This polarity commonly translates into different tissues developing on each side of the leaf blade. This is important because it promotes better photosynthetic efficiency as related to light absorption and gas exchange. Many researchers have studied the molecular bases of the emergence of leaf abaxial-adaxial polarity, showing that it is produced by the interaction and differential expression of particular genes and other molecules. However, until now, it is still unclear if the molecular components documented thus far are sufficient to explain the emergence of leaf polarity. In this work, we integrated the available experimental data to construct a graph of the Gene Regulatory Network (GRN) involved in the formation of abaxial-adaxial polarity in the leaf primordium of