AUTHOR=Orlinick Benjamin L. , Smith Angela , Medley Kim A. , Westby Katie M. TITLE=Genetically based variation in heat tolerance covaries with climate in a globally important disease vector JOURNAL=Frontiers in Ecology and Evolution VOLUME=11 YEAR=2024 URL=https://www.frontiersin.org/journals/ecology-and-evolution/articles/10.3389/fevo.2023.1248673 DOI=10.3389/fevo.2023.1248673 ISSN=2296-701X ABSTRACT=Introduction

Vector-borne diseases (VBDs) are an increasingly important global health concern in the face of climate change. Understanding the ecology and evolution of vector species is critical to predicting and combating VBD. Vectorial capacity models, used to forecast disease transmission, traditionally assume traits are constant among populations, and little is known about whether different vector populations vary in thermal tolerance. To test for geographic variation in upper thermal tolerance, we determined the critical thermal maximum (CTmax) of Aedes albopictus, a globally distributed mosquito and competent vector for many viruses including West Nile, chikungunya, and dengue.

Methods

We studied CTmax for eight different populations spanning four climate zones across the Eastern United States using common garden experiments to isolate genetic variation. To explore potential drivers of this variation we then tested the relationship between climatic variables measured near each population source and CTmax.

Results

We found significant differences across populations for both adults and larvae, and these differences were more pronounced for adults. Larvae had higher CTmax values compared to adults. Several climatic variables improved models of CTmax for both adults and larvae including mean and max seasonal temperature, annual precipitation, and relative humidity. Annual precipitation appears to be particularly important and has a positive linear relationship with CTmax.

Discussion

The differences between life stages likely result from different selection pressures experienced in their terrestrial and aquatic habitats. Importantly, the assumption that mosquito populations within a species have the same upper thermal limits does not hold in this case, thus it is important to use population-specific CTmax values, among other important physiological parameters that may vary, to more accurately model and forecast VBDs.