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REVIEW article
Front. Drug Saf. Regul.
Sec. Respiratory Drug Safety
Volume 5 - 2025 | doi: 10.3389/fdsfr.2025.1528468
This article is part of the Research TopicSafety of Corticosteroids in Respiratory MedicineView all 5 articles
Corticosteroids in Lung Cancer
Provisionally accepted- 1Clinic for Pulmonology, University Clinical Center of Serbia, Belgrade, Serbia
- 2Municipal Institute for Lung Diseases and TB, Belgrade, Serbia
- 3Internal Medicine Clinic „Akta Medica“, Belgrade, Serbia
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Despite significant advances in lung cancer treatment, patients with this disease still present with multiple symptoms which that are very hard to control. Corticosteroids are widely used in patients with lung cancer, but without clear evidence for their efficacy. Thus, corticosteroids have been used for the treatment of conditions arisen arising due to the tumor itself, adverse effects of the applied specific therapy and for symptom palliation. In this review we are going to summarize clinical indications for corticosteroid use in patients with lung cancer: malignant airway obstruction, superior vena cava syndrome, brain metastases, treatment-related adverse events, anorexia and cachexia, fatigue, dyspnea, nausea and vomiting, spinal cord compression, and pain.
Keywords: corticosteroids, lung cancer, Immunotherapy, Pain, Cachexia, Dyspnea, Nausea and vomiting, brain metastases
Received: 14 Nov 2024; Accepted: 07 Apr 2025.
Copyright: © 2025 Ćeriman Krstić, Gajić, Djukanović and Jovanovic. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Vesna Ćeriman Krstić, Clinic for Pulmonology, University Clinical Center of Serbia, Belgrade, Serbia
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.