AUTHOR=Mugelli Alessandro , Tamargo Juan TITLE=Editorial: Substance-based medical devices for human health: a challenge of efficacy, safety, and sustainability JOURNAL=Frontiers in Drug Safety and Regulation VOLUME=3 YEAR=2023 URL=https://www.frontiersin.org/journals/drug-safety-and-regulation/articles/10.3389/fdsfr.2023.1222790 DOI=10.3389/fdsfr.2023.1222790 ISSN=2674-0869