Frontiers in Drug Discovery

Original Research

Published on 18 Dec 2023

Global proteomics insights for a novel small compound targeting the non-integrin Laminin Receptor in a macrophage cell model

Abigail Haffner
Manoel Figueiredo Neto
C. Samuel Umbaugh
Tiago J. P. Sobreira
Timothy B. Lescun
Herman O. Sintim
Marxa L. Figueiredo

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1326736

1,324 views
1 citation

Review

Published on 15 Dec 2023

Targeting mitochondrial metabolites and nucleic acids as an anti-inflammatory strategy

Yukun Min
Luke A. J. O’Neill

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1294454

1,821 views

Original Research

Published on 11 Dec 2023

Consensus docking aid to model the activity of an inhibitor of DNA methyltransferase 1 inspired by de novo design

Diana L. Prado-Romero
Alejandro Gómez-García
Raziel Cedillo-González
Hassan Villegas-Quintero
Juan F. Avellaneda-Tamayo
Edgar López-López
Fernanda I. Saldívar-González
Ana L. Chávez-Hernández
José L. Medina-Franco

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1261094

3,383 views
5 citations

Case Report

Published on 11 Dec 2023

Case report: C-reactive protein apheresis in cardiogenic shock: case series from the C-reactive protein apheresis in acute myocardial infarction-registry

J. Torzewski
S. Mattecka
W. Ries
C. D. Garlichs
F. Heigl
J. Fiedler
A. Sheriff

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1286710

2,294 views
2 citations

Editorial

Published on 08 Dec 2023

Editorial: Drug discovery for emerging and neglected tropical diseases: advances, challenges and perspectives

Laura Alcântara
Caio Franco
Nilmar Moretti
Denise Pilger

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1346042

972 views

Review

Published on 01 Dec 2023

Latest development of approved COVID-19 drugs and COVID-19 drugs undergoing late stage clinical trials

Bingru Feng
Kai Fu

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1304129

2,453 views
1 citation

Mini Review

Published on 30 Nov 2023

Introduction to small molecule drug discovery and preclinical development

Michelle W. Y. Southey
Michael Brunavs

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1314077

37,453 views
17 citations

Mini Review

Published on 27 Nov 2023

HyBryte™ use in early-stage cutaneous T-cell lymphoma

Brian Poligone
Carolina V. Alexander-Savino
Ellen J. Kim
Aaron R. Mangold
Jennifer Desimone
Henry K. Wong
Adam T. Rumage
Oreola Donini
Andrea Haulenbeek
Christopher J. Schaber

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1298453

2,084 views

Editorial

Published on 23 Nov 2023

Editorial: Advances in anti-malarial drug discovery

Agam Prasad Singh
Brijesh Rathi

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1335842

1,097 views
1 citation

Original Research

Published on 22 Nov 2023

Targeting a cancer-specific LYPD3 glycoform for tumor therapy

Theresa Neumann
Evelyn Hartung
Johanna Gellert
Lisa Weiß
Manon Weiske
Naomi Kast
Stephanie Gurka
Sophie Marinoff
Anika Jäkel
Antje Danielczyk

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1298916

2,774 views
1 citation

Review

Published on 21 Nov 2023

Future treatments for the arteriopathy of ectopic calcification disorders

Benjamin M. Davies
Frank Rutsch
Naren Vyavahare
Alexander Jones

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1249966

1,788 views

Original Research

Published on 14 Nov 2023

In vitro drug interaction of ionophores with artemisinin and chloroquine against Plasmodium falciparum 3D7 blood-stage infection

Vinoth Rajendran
Keerthana Gurukkalot

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1257698

1,304 views

Original Research

Published on 30 Oct 2023

An improved method for large scale generation and high-throughput functional characterization of human iPSC-derived microglia

Manisha Padmakumar
Steven Biesmans
Jorge S. Valadas
Jan R. Detrez
Gaëlle Gillet
Priscillia Bresler
Marie-Laure Clénet
Irena Kadiu

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1289314

2,129 views

Review

Published on 18 Sep 2023

State-of-the-art strategies to prioritize Mycobacterium tuberculosis drug targets for drug discovery using a subtractive genomics approach

Adetutu Akinnuwesi
Samuel Egieyeh
Ruben Cloete

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1254656

1,939 views
1 citation

Mini Review

Published on 05 Sep 2023

Harnessing bioluminescence for drug discovery and epigenetic research

Hannah J. Gleneadie
Andrew Dimond
Amanda G. Fisher

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1249507

2,805 views
2 citations

Brief Research Report

Published on 03 Aug 2023

Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics

Ida Lin
Peter B. Rupert
Kristina Pilat
Raymond O. Ruff
Della J. Friend
Man Kid Chan
Midori Clarke
Benjamin G. Hoffstrom
Jane Carter
Soheil Meshinchi

Frontiers in Drug Discovery

doi 10.3389/fddsv.2023.1216516

3,907 views
3 citations