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133 articles

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Articles

Original Research

Published on 14 Jan 2022

Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism

in Neurological Drugs

Christopher R. Apostol
Kelsey Bernard
Parthasaradhireddy Tanguturi
Gabriella Molnar
Mitchell J. Bartlett
Lajos Szabò
Chenxi Liu
J. Bryce Ortiz
Maha Saber
Katherine R. Giordano

Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.818003

6,086 views
11 citations

Review

Published on 11 Nov 2021

Harnessing the Potential of Human Pluripotent Stem Cell-Derived Motor Neurons for Drug Discovery in Amyotrophic Lateral Sclerosis: From the Clinic to the Laboratory and Back to the Patient

in Neurological Drugs

Nuno Jorge Lamas
Laurent Roybon

Harnessing the Potential of Human Pluripotent Stem Cell-Derived Motor Neurons for Drug Discovery in Amyotrophic Lateral Sclerosis: From the Clinic to the Laboratory and Back to the Patient

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.773424

5,593 views
12 citations

Original Research

Published on 27 Oct 2021

Deep Learning Prediction of Adverse Drug Reactions in Drug Discovery Using Open TG–GATEs and FAERS Databases

in In silico Methods and Artificial Intelligence for Drug Discovery

Attayeb Mohsen
Lokesh P. Tripathi
Kenji Mizuguchi

Deep Learning Prediction of Adverse Drug Reactions in Drug Discovery Using Open TG–GATEs and FAERS Databases

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.768792

12,042 views
25 citations

Field Grand Challenge

Published on 28 Jul 2021

Post-Pandemic Drug Discovery and Development: Facing Present and Future Challenges

Bruno O. Villoutreix

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.728469

11,580 views
11 citations

Specialty Grand Challenge

Published on 28 Jul 2021

Grand Challenges of Computer-Aided Drug Design: The Road Ahead

in In silico Methods and Artificial Intelligence for Drug Discovery

José L. Medina-Franco

Grand Challenges of Computer-Aided Drug Design: The Road Ahead

Frontiers in Drug Discovery

doi 10.3389/fddsv.2021.728551

17,344 views
33 citations