AUTHOR=Dagliati Arianna , Tibollo Valentina , Sacchi Lucia , Malovini Alberto , Limongelli Ivan , Gabetta Matteo , Napolitano Carlo , Mazzanti Andrea , De Cata Pasquale , Chiovato Luca , Priori Silvia , Bellazzi Riccardo TITLE=Big Data as a Driver for Clinical Decision Support Systems: A Learning Health Systems Perspective JOURNAL=Frontiers in Digital Humanities VOLUME=5 YEAR=2018 URL=https://www.frontiersin.org/journals/digital-humanities/articles/10.3389/fdigh.2018.00008 DOI=10.3389/fdigh.2018.00008 ISSN=2297-2668 ABSTRACT=

Big data technologies are nowadays providing health care with powerful instruments to gather and analyze large volumes of heterogeneous data collected for different purposes, including clinical care, administration, and research. This makes possible to design IT infrastructures that favor the implementation of the so-called “Learning Healthcare System Cycle,” where healthcare practice and research are part of a unique and synergic process. In this paper we highlight how “Big Data enabled” integrated data collections may support clinical decision-making together with biomedical research. Two effective implementations are reported, concerning decision support in Diabetes and in Inherited Arrhythmogenic Diseases.