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REVIEW article
Front. Digit. Health
Sec. Health Informatics
Volume 7 - 2025 | doi: 10.3389/fdgth.2025.1507967
This article is part of the Research Topic Electronic Health Records in Emergency Medicine: From Accountability to Opportunity View all articles
A Call to Action for Adverse Drug Event (ADE) Detection and Prevention
Provisionally accepted- 1 United States Pharmacopeial Convention, Rockville, United States
- 2 Pharmacy HIT Collaborative, Alexandria, United States
- 3 University of Maryland, College Park, College Park, Maryland, United States
Injury from medication use, known as an adverse drug event (ADE) accounts for millions of emergency department visits globally and thousands of hospitalizations annually within the United States. Efforts to prevent and detect ADEs within healthcare systems are complicated by data quality, lack of data standardization, and actionable clinical decision support systems. United States Pharmacopeia (USP) proposes the use of an ADE value set, a standardized grouping of medical terms, to improve the identification, documentation, and use of ADE information in EHRs. Artificial Intelligence and Machine Learning capabilities would be further strengthened through the standardization of ADE data and information.
Keywords: allergy, intolerance, patient history, healthcare, standardization
Received: 10 Oct 2024; Accepted: 05 Feb 2025.
Copyright: © 2025 McCue, Spiro, Guharoy, Butler and Love. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
John McCue, United States Pharmacopeial Convention, Rockville, United States
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