Amarech Kindie ¹ Desta Debalkie Atnafu ² Habtamu Alganeh Guadie ^3*

• ¹ Amhara Regional Health Bureau, Bahir Dar, Amhara Region, Ethiopia
• ² Department of Health Systems Managemnt and Health Economics, School of Public health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia
• ³ School of Public Health, College of Medicine and Health sciences, Bahir Dar University, Bahir Dar, Amhara Region, Ethiopia

The District Health Information System version 2 ( DHIS2) is an open-source platform designed for data collection, processing, analysis, and visualization within healthcare systems. However, there is limited empirical evidence regarding health professionals' intentions to use district health information systems. Understanding the factors influencing health workers' intention to utilize DHIS2 is crucial for ensuring successful implementation and sustained usage.This study aimed to assess the intention to use DHIS2 and identify associated factors among health professionals in health centers of Bahir Dar Metropolitan City, Ethiopia, in 2022.Methods: An institutional-based cross-sectional study was conducted involving 368 randomly selected health professionals from health centers in Bahir Dar City, Ethiopia, between May 24 and June 24, 2022. Data were collected using a structured, self-administered questionnaire. Completed questionnaires were entered and coded in EpiData version 4.6 and exported to SPSS version 25 for cleaning and statistical analysis. Descriptive statistics, bivariate, and multivariable logistic regression analyses were performed. Model fitness was assessed using the Hosmer and Lemeshow goodness-of-fit test, with statistical significance set at p-value < 0.05 and a 95% confidence interval.Results: A total of 342 participants completed the study, resulting in a response rate of 92.9%.The sample included 176 (51.5%) females, and 147 (43%) were nurses. Nearly two-thirds (65.2%) of health professionals expressed an intention to use the DHIS2 system. Intention to use DHIS2 was significantly associated with factors including attitude, computer skills, perceived utility, and perceived ease of use.The findings indicate that attitude, perceived utility, perceived ease of use, and computer skills significantly influence the intention to utilize DHIS2. Therefore, it is imperative to implement targeted interventions prior to system rollout, including practice-based training, fostering positive attitudes, and enhancing knowledge of the system's usability and functionality to improve the adoption of the district health information system.