AUTHOR=Mezzetti Maura , Ryan Colleen P. , Balestrucci Priscilla , Lacquaniti Francesco , Moscatelli Alessandro TITLE=Bayesian hierarchical models and prior elicitation for fitting psychometric functions JOURNAL=Frontiers in Computational Neuroscience VOLUME=17 YEAR=2023 URL=https://www.frontiersin.org/journals/computational-neuroscience/articles/10.3389/fncom.2023.1108311 DOI=10.3389/fncom.2023.1108311 ISSN=1662-5188 ABSTRACT=

Our previous articles demonstrated how to analyze psychophysical data from a group of participants using generalized linear mixed models (GLMM) and two-level methods. The aim of this article is to revisit hierarchical models in a Bayesian framework. Bayesian models have been previously discussed for the analysis of psychometric functions although this approach is still seldom applied. The main advantage of using Bayesian models is that if the prior is informative, the uncertainty of the parameters is reduced through the combination of prior knowledge and the experimental data. Here, we evaluate uncertainties between and within participants through posterior distributions. To demonstrate the Bayesian approach, we re-analyzed data from two of our previous studies on the tactile discrimination of speed. We considered different methods to include a priori knowledge in the prior distribution, not only from the literature but also from previous experiments. A special type of Bayesian model, the power prior distribution, allowed us to modulate the weight of the prior, constructed from a first set of data, and use it to fit a second one. Bayesian models estimated the probability distributions of the parameters of interest that convey information about the effects of the experimental variables, their uncertainty, and the reliability of individual participants. We implemented these models using the software Just Another Gibbs Sampler (JAGS) that we interfaced with R with the package rjags. The Bayesian hierarchical model will provide a promising and powerful method for the analysis of psychometric functions in psychophysical experiments.