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ORIGINAL RESEARCH article

Front. Clin. Diabetes Healthc.
Sec. Diabetes Clinical Epidemiology
Volume 5 - 2024 | doi: 10.3389/fcdhc.2024.1449641

Original article; adage et al Predictors of Glycemic Control among Type 1 Pediatrics Diabetes Patients; North East Ethiopia

Provisionally accepted
Hiwot Adege Hiwot Adege 1Gedefaw Getnet Gedefaw Getnet 2Abyou Seyfu Ambaye Abyou Seyfu Ambaye 3Mekuanint Terefe Kassa Mekuanint Terefe Kassa 4Bedilu Linger Endalifer Bedilu Linger Endalifer 5*
  • 1 School of Medicine, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia
  • 2 School of Pharmacy, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia
  • 3 Departement of Pharmacy, Asrat Woldeyes Health Science Campus, Debre Berhan University, Debre Berhan, Ethiopia, Debre Berhan, Ethiopia
  • 4 School of Medicine, Asrat Woldeyes Health Science Campus, Debre Berhan University, Debre Berhan, Ethiopia, Debre Berhan, Ethiopia
  • 5 Departement of Pharmacy, Asrat Woldeyes Health Science Campus, Debre Berhan University, Debre Berhan, Ethiopia., Debre Berhan, Ethiopia

The final, formatted version of the article will be published soon.

    Introduction: Type 1 diabetes mellitus is the most common endocrine-metabolic disorder in children and adolescents worldwide. This study aims to determine metabolic glycemic control levels and predictors among pediatric type 1 diabetes patients Methods: Institution based prospective cross-sectional study was conducted from July 01, 2022, to October 30, 2022, attending pediatric chronic follow up at Dessie Comprehensive Specialized Hospital, North East Ethiopia. Patients on follow-up for more than 3 months and aged under 18 years were enrolled in the study consecutively based on their visits. Data were entered into Epidata version 3.1 and exported to SPSS version 26 for analysis. Bivariate and multivariate analysis was done to identify factors affecting glycemic control.Result: Among 203 patients with type 1 diabetes, the average age was 8.72 ± 4.25 years, with the largest group of participants being over 10 years old (77 patients, 37%). The majority of the patients were female, totaling 126 (62.1%), and about 69 (34.0%) were in grades 7-10.Retinopathy, nephropathy, and diabetic ketoacidosis were commonly observed diabetic-related complications in this study. More than half of the patients, 107 (52.7%), had good diabetic control, while 96 (47.3%) had poor diabetic control. Factors significantly associated with poor glycemic control include having diabetes for more than five years (aOR 1.45, 95% CI 0.47, 0.91), being a third-born child (aOR 0.22, 95% CI 0.05, 0.92), having a comorbid disease condition (aOR 1.84, 95% CI 0.29, 0.92), and experiencing diabetes-related complications (aOR 0.26, 95% CI 0.08, 0.97).The study found that glycemic control is significantly poor among pediatric patients with type 1 diabetes. As a result, these patients require special attention to prevent the long-term consequences of diabetes.

    Keywords: glycemic control, Pediatrics, Type 1 DM, Northeast, Ethiopia

    Received: 08 Jul 2024; Accepted: 20 Dec 2024.

    Copyright: © 2024 Adege, Getnet, Ambaye, Kassa and Endalifer. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Bedilu Linger Endalifer, Departement of Pharmacy, Asrat Woldeyes Health Science Campus, Debre Berhan University, Debre Berhan, Ethiopia., Debre Berhan, Ethiopia

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.