Intermolecular Interaction Studies in Binary and Higher Order Liquid Mixtures, Ionic Liquids and Deep Eutectic Solvents (DES) Based Systems

RANJAN DEY ^*

• DEPT OF CHEMISTRY, BITS PILANI K K BIRLA GOA CAMPUS, GOA, INDIA, SOUTH GOA, India

mixture especially those comprising Ionic Liquids (ILs) and Deep Eutectic Solvents (DES) are crucial for understanding their behavior in various industrial and scientific applications.Understanding the thermophysical properties and the nature of these intermolecular interactions is essential for optimizing the use of this binary and multicomponent mixture and consequently the usage of sustainable and greener alternative in various applications in the form of ILs and DESs, including drug delivery systems, solvent recovery processes, etc. while ensuring improved efficiency, safety, and performance in practical implementations. As of today, there are more than approximately 500 commercially available Room temperature Ionic Liquids (RTILs) with multifarious commercial and industrial applications and are used in diverse processes viz., solvent extraction [ https://doi.org/10.1016/j.jics.2025.101638] , separations, heat-mass transfer, process design etc. Thorough knowledge of the thermophysical properties of the ionic liquids and their phase behaviour with solids, liquids and gases opens up newer pathways for designing "tailormade" ionic liquids which can be fine-tuned to carry out very specific technical applications as a designer solvent. The high thermal stability, very low vapour pressure, adjustable viscosity and water miscibility make them ideally suited environmentally benign alternatives as compared to conventional organic solvents and thereby can be termed as Green Solvents.Deep Eutectic solvents represent the emerging "New Age Green Solvents", owing to their very low melting points depression in the eutectic region. They are slowly gaining ground as the alternatives to the Ionic Liquids owing to their specific characteristics of being safer This Special Issue of Frontiers aims to bring forth these aspects to make it interesting for a diverse scientific community.