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MINI REVIEW article
Front. Chem.
Sec. Analytical Chemistry
Volume 13 - 2025 |
doi: 10.3389/fchem.2025.1536209
This article is part of the Research Topic Recent Advances in Pharmaceutical Analysis: Applications and New Challenges for the Quality of Medicines View all 10 articles
The Usefulness of Infrared Spectroscopy and X-ray Powder Diffraction in the Analysis of Falsified, Illegal, and Medicinal Products
Provisionally accepted- National Medicines Institute (Poland), Warsaw, Poland
One way to combat the black pharmaceutical market is to exchange experience and knowledge among the laboratories involved in this fight. A beneficial approach is compiling application examples that demonstrate the development and growing potential of the two analytical techniques that are undoubtedly useful in investigating pharmacologically active ingredients found in products dangerous to consumers health and life. Attenuated total reflectance Fourier transform infrared spectroscopy and X-ray powder diffraction are nondestructive techniques substantial for examining evidence seized by the police, demanding minimal preparation of the sample. Importantly, they are among the few that do not negatively impact the environment because they do not require the production or disposal of chemical reagents or solvents, aligning with the principles of green chemistry. Both techniques provide consistent, reproducible results, essential for legal and scientific validity.
Keywords: falsified medicinal products, Illegal substances, API, Analytical Chemistry, FTIR, ATR, XRPD
Received: 28 Nov 2024; Accepted: 03 Feb 2025.
Copyright: © 2025 Mocarska, Piorunska, Maurin and Blazewicz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Karolina Piorunska, National Medicines Institute (Poland), Warsaw, Poland
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