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REVIEW article

Front. Chem.
Sec. Nanoscience
Volume 12 - 2024 | doi: 10.3389/fchem.2024.1492215
This article is part of the Research Topic Metal-based Nanomaterials for Tumor Diagnosis and Therapy View all articles

Nanomaterial-Based Cancer Immunotherapy: Enhancing Treatment Strategies

Provisionally accepted
Mengxiang Tian Mengxiang Tian *Xionglin Liu Xionglin Liu *Haiping Pei Haiping Pei
  • xiangya hosipital, Changsha, China

The final, formatted version of the article will be published soon.

    Cancer immunotherapy has emerged as a pivotal approach for treating various types of cancer, incorporating strategies such as chimeric antigen receptor T-cell (CAR-T) therapy, immune checkpoint blockade therapy, neoantigen peptides, mRNA vaccines, and small molecule modulators. However, the clinical efficacy of these therapies is frequently constrained by significant adverse effects and limited therapeutic outcomes.In recent years, the integration of nanotechnology into cancer immunotherapy has gained considerable attention, showcasing notable advantages in drug delivery, targeted accumulation, controlled release, and localized administration. This review focuses on nanomaterial-based immunotherapeutic strategies, particularly the development and application of nanocarriers such as liposomes, lipid nanoparticles, polymeric nanoparticles, and self-assembling scaffolds. We examine how these strategies can enhance the efficacy of cancer immunotherapy while minimizing adverse effects and analyze their potential for clinical translation.

    Keywords: nanomaterials, cancer immunotherapy, Drug delivery, Precision targeting, CAR-T therapy

    Received: 06 Sep 2024; Accepted: 30 Sep 2024.

    Copyright: © 2024 Tian, Liu and Pei. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Mengxiang Tian, xiangya hosipital, Changsha, China
    Xionglin Liu, xiangya hosipital, Changsha, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.