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MINI REVIEW article

Front. Chem.
Sec. Supramolecular Chemistry
Volume 12 - 2024 | doi: 10.3389/fchem.2024.1478034
This article is part of the Research Topic Supramolecular Cancer Therapeutic Biomaterials-Volume II View all articles

Recent advances in cancer detection using dynamic, stimuli-responsive supramolecular chemosensors. A focus review

Provisionally accepted
Kotaro Matsumoto Kotaro Matsumoto 1Keiichi Nakagawa Keiichi Nakagawa 2Daisuke Asanuma Daisuke Asanuma 2Gaku Fukuhara Gaku Fukuhara 1*
  • 1 Tokyo Institute of Technology, Meguro City, Japan
  • 2 The University of Tokyo, Bunkyo, Tōkyō, Japan

The final, formatted version of the article will be published soon.

    In current chemistry, supramolecular materials that respond to a wide variety of external stimuli, such as solvents, temperature, light excitation, pH, and mechanical forces (pressure, stress, strain, and tension), have attracted considerable attention; for example, we have developed cyclodextrins, cucurbiturils, pillararenes, calixarenes, crown ether-based chemical sensors, or chemosensors. These supramolecular chemosensors have potential applications in imaging, probing, and cancer detection. Recently, we focused on pressure, particularly solution-state hydrostatic pressure, from the viewpoint of cancer therapy. This Mini Review summarizes (i) why hydrostatic pressure is important, particularly in biology, and (ii) what we can do using hydrostatic pressure stimulation.

    Keywords: mechanobiology, supramolecular chemistry, Hydrostatic Pressure, Living cell, Chemosensor

    Received: 09 Aug 2024; Accepted: 23 Sep 2024.

    Copyright: © 2024 Matsumoto, Nakagawa, Asanuma and Fukuhara. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Gaku Fukuhara, Tokyo Institute of Technology, Meguro City, Japan

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.