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REVIEW article

Front. Chem.
Sec. Organic Chemistry
Volume 12 - 2024 | doi: 10.3389/fchem.2024.1470861
This article is part of the Research Topic Green Processes for the Synthesis of Heterocycles View all 6 articles

Novel Transition Metal Free Synthetic Protocols Towards the Construction of 2,3-Dihydrobenzofurans: A Recent Update

Provisionally accepted
Aqsa Mushtaq Aqsa Mushtaq 1*Ameer Fawad Zahoor Ameer Fawad Zahoor 1*Muhammad Irfan Muhammad Irfan 1Atta Ul Haq Atta Ul Haq 1*Dr Samreen Gul Khan Dr Samreen Gul Khan 1Bushra Parveen Bushra Parveen 1*Dr. Ali Irfan Dr. Ali Irfan 1Katarzyna Kotwica-Mojzych Katarzyna Kotwica-Mojzych 2Mariola Głowacka Mariola Głowacka 3Mariusz Mojzych Mariusz Mojzych 3*
  • 1 Government College University, Faisalabad, Faisalabad, Pakistan
  • 2 Medical University of Lublin, Lublin, Lublin, Poland
  • 3 The Mazovian Academy in Plock, Plock, Poland

The final, formatted version of the article will be published soon.

    2,3-Dihydrobenzofurans are noteworthy scaffolds in organic and medicinal chemistry, constituting the structural framework of many of the varied medicinally active organic compounds. Moreover, a diverse variety of biologically potent natural products are also embodied with this heterocyclic nucleus. Reflecting on the wide biological substantiality of dihydrobenzofurans, several innovative and facile synthetic developments are constantly evolving to achieve these heterocycles. This review summarizes the transition metal free, efficient and novel synthetic pathways towards the construction of dihydrobenzofuran nucleus, established post 2020.

    Keywords: Dihydrobenzofurans, Transition metal free, Photocatalytic, Organocatalyzed, Catalyst free

    Received: 26 Jul 2024; Accepted: 31 Oct 2024.

    Copyright: © 2024 Mushtaq, Zahoor, Irfan, Haq, Samreen Gul Khan, Parveen, Irfan, Kotwica-Mojzych, Głowacka and Mojzych. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Aqsa Mushtaq, Government College University, Faisalabad, Faisalabad, Pakistan
    Ameer Fawad Zahoor, Government College University, Faisalabad, Faisalabad, Pakistan
    Atta Ul Haq, Government College University, Faisalabad, Faisalabad, Pakistan
    Bushra Parveen, Government College University, Faisalabad, Faisalabad, Pakistan
    Mariusz Mojzych, The Mazovian Academy in Plock, Plock, Poland

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.