AUTHOR=Li Ya-Nan , Wang Bin , Huang Ye-Kai , Hu Jin-Song , Sun Jia-Nan TITLE=Recent advances in metal catalyst- and oxidant-free electrochemical C-H bond functionalization of nitrogen-containing heterocycles JOURNAL=Frontiers in Chemistry VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.967501 DOI=10.3389/fchem.2022.967501 ISSN=2296-2646 ABSTRACT=

The C-H functionalization of nitrogen-containing heterocycles has emerged as a powerful strategy for the construction of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds. In order to achieve efficient and selective C-H functionalization, electrochemical synthesis has attracted increasing attention. Because electrochemical anodic oxidation is ideal for replacing chemical reagents in C-H functionalization reactions. This mini-review summarizes the current knowledge and recent advances since 2017 in the synthetic utility of electrochemical transformations for the C-H functionalization of nitrogen-containing heterocycles.