AUTHOR=Cheng Xiamin , Yan Hui , Pang Songhao , Ya Mingjun , Qiu Feng , Qin Pinzhu , Zeng Chao , Lu Yongna TITLE=Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products JOURNAL=Frontiers in Chemistry VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.963004 DOI=10.3389/fchem.2022.963004 ISSN=2296-2646 ABSTRACT=

Although medicinal natural products and their derivatives have shown promising effects in disease therapies, they usually suffer the drawbacks in low solubility and stability in the physiological environment, low delivery efficiency, side effects due to multi-targeting, and low site-specific distribution in the lesion. In this review, targeted delivery was well-guided by liposomal formulation in the aspects of preparation of functional liposomes, liposomal medicinal natural products, combined therapies, and image-guided therapy. This review is believed to provide useful guidance to enhance the targeted therapy of medicinal natural products and their derivatives.