AUTHOR=Babaei Elaheh , Küçükkılınç Tuba Tüylü , Jalili-Baleh Leili , Nadri Hamid , Öz Esin , Forootanfar Hamid , Hosseinzadeh Elaheh , Akbari Tayebeh , Ardestani Mehdi Shafiee , Firoozpour Loghman , Foroumadi Alireza , Sharifzadeh Mohammad , Mirjalili Bi Bi Fatemeh , Khoobi Mehdi 

TITLE=Novel Coumarin–Pyridine Hybrids as Potent Multi-Target Directed Ligands Aiming at Symptoms of Alzheimer’s Disease

JOURNAL=Frontiers in Chemistry

VOLUME=10

YEAR=2022

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.895483

DOI=10.3389/fchem.2022.895483

ISSN=2296-2646

ABSTRACT=<title>Graphical Abstract</title><p>A novel series of 3-phenyl-coumarin derivatives containing pyridinium salts was prepared, indicating significant inhibitory activity against AChE and BuChE as well as precious neuroprotective and anti-Aβ aggregation effects.<graphic xlink:href="FCHEM_fchem-2022-895483_wc_abs.tif" position="anchor" xmlns:xlink="http://www.w3.org/1999/xlink" /></p>