AUTHOR=Liu Xin , Liu Dan , Muschin Tegshi , Bao Agula , Bai Chaolumen , Bao Yong-Sheng 

TITLE=Supported Palladium Nanoparticles Catalyzed Intermolecular Carbopalladation of Nitriles and Organoboron Compounds

JOURNAL=Frontiers in Chemistry

VOLUME=10

YEAR=2022

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.855850

DOI=10.3389/fchem.2022.855850

ISSN=2296-2646

ABSTRACT=<p>The first heterogeneous catalyzed example for the direct synthesis of aromatic ketones via intermolecular carbopalladation of aliphatic nitriles and organoboron compounds was developed. This mild method proceeds with a supported palladium nanoparticles catalyst that could be reused and recycled five times. The fresh and used catalysts were characterized by XPS and TEM. The XPS analysis indicated that Pd<sup>0</sup> was the active species for the reaction. This methodology provides a mild and cost-effective strategy for the efficient synthesis of ketones.</p>