AUTHOR=Kazemzadeh Parya , Sayadi Khalil , Toolabi Ali , Sayadi Jalil , Zeraati Malihe , Chauhan Narendra Pal Singh , Sargazi Ghasem 

TITLE=Structure-Property Relationship for Different Mesoporous Silica Nanoparticles and its Drug Delivery Applications: A Review

JOURNAL=Frontiers in Chemistry

VOLUME=10

YEAR=2022

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.823785

DOI=10.3389/fchem.2022.823785

ISSN=2296-2646

ABSTRACT=<p>Mesoporous silica nanoparticles (MSNs) are widely used as a promising candidate for drug delivery applications due to silica’s favorable biocompatibility, thermal stability, and chemical properties. Silica’s unique mesoporous structure allows for effective drug loading and controlled release at the target site. In this review, we have discussed various methods of MSNs’ mechanism, properties, and its drug delivery applications. As a result, we came to the conclusion that more <italic>in vivo</italic> biocompatibility studies, toxicity studies, bio-distribution studies and clinical research are essential for MSN advancement.</p>