AUTHOR=Wang Wenli , Li Yuxin , He Ye , Jiang Xing , Yi Ying , Zhang Xihan , Zhang Shiyu , Chen Guangtong , Yang Min , Luo Jia-Lie , Fan Boyi TITLE=Progress in the total synthesis of resin glycosides JOURNAL=Frontiers in Chemistry VOLUME=10 YEAR=2022 URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2022.1036954 DOI=10.3389/fchem.2022.1036954 ISSN=2296-2646 ABSTRACT=

Resin glycosides, mainly distributed in plants of the family Convolvulaceae, are a class of novel and complex glycolipids. Their structural complexity and significant biological activities have received much attention from synthetic chemists, and a number of interesting resin glycosides have been synthesized. The synthesized resin glycosides and their analogues not only helped in structural verification, structural modification, and further biological activity exploration but also provided enlightenment for the synthesis of glycoside compounds. Herein, the present review summarizes the application of various efforts toward the synthesis of resin glycosides in the last decade.