AUTHOR=Li Bingxin , Pan Luyao , Zhang Haofeng , Xie Lingping , Wang Xi , Shou Jiahui , Qi Yu , Yan Xiaojian 

TITLE=Recent Developments on Using Nanomaterials to Combat Candida albicans

JOURNAL=Frontiers in Chemistry

VOLUME=9

YEAR=2021

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2021.813973

DOI=10.3389/fchem.2021.813973

ISSN=2296-2646

ABSTRACT=<p>Vaginal candidiasis (VC) is a common disease of women and the main pathogen is <italic>Candida albicans</italic> (<italic>C. albicans</italic>). <italic>C. albicans</italic> infection incidence especially its drug resistance have become a global health threat due to the existence of <italic>C. albicans</italic> biofilms and the low bioavailability of traditional antifungal drugs. In recent years, nanomaterials have made great progresses in the field of antifungal applications. Some researchers have treated fungal infections with inorganic nanoparticles, represented by silver nanoparticles (AgNPs) with antifungal properties. Liposomes, polymeric nanoparticles, metal-organic frameworks (MOFs), and covalent organic frameworks (COFs) were also used to improve the bioavailability of antifungal drugs. Herein, we briefly introduced the recent developments on using above nanomaterials to combat <italic>C. albicans</italic> in antifungal applications.</p>