AUTHOR=Xu Zhenglei , Peng Minsi , Zhang Zhuliang , Zeng Haotian , Shi Ruiyue , Ma Xiaoxin , Wang Lisheng , Liao Bihong TITLE=Graphene-Assisted Electrochemical Sensor for Detection of Pancreatic Cancer Markers JOURNAL=Frontiers in Chemistry VOLUME=9 YEAR=2021 URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2021.733371 DOI=10.3389/fchem.2021.733371 ISSN=2296-2646 ABSTRACT=

Pancreatic cancer is a highly lethal gastrointestinal malignancy. Most patients are already in the middle to advanced stages of pancreatic cancer at the time of diagnosis and cannot be treated completely. As a single-atom planar two-dimensional crystal, graphene’s unusual electronic structure, specific electronic properties and excellent electron transport capacity make it uniquely advantageous in the field of electrochemical sensing. In this mini-review, we summarize the potential application of graphene in pancreatic cancer detection. K-Ras gene, CEA and MicroRNA are important in the early diagnosis of pancreatic cancer.