AUTHOR=Dong Shixian , Feng Sijia , Chen Yuzhou , Chen Mo , Yang Yimeng , Zhang Jian , Li Huizhu , Li Xiaotong , Ji Liang , Yang Xing , Hao Yuefeng , Chen Jun , Wo Yan TITLE=Nerve Suture Combined With ADSCs Injection Under Real-Time and Dynamic NIR-II Fluorescence Imaging in Peripheral Nerve Regeneration in vivo JOURNAL=Frontiers in Chemistry VOLUME=9 YEAR=2021 URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2021.676928 DOI=10.3389/fchem.2021.676928 ISSN=2296-2646 ABSTRACT=
Peripheral nerve injury gives rise to devastating conditions including neural dysfunction, unbearable pain and even paralysis. The therapeutic effect of current treatment for peripheral nerve injury is unsatisfactory, resulting in slow nerve regeneration and incomplete recovery of neural function. In this study, nerve suture combined with ADSCs injection was adopted in rat model of sciatic nerve injury. Under real-time visualization of the injected cells with the guidance of NIR-II fluorescence imaging