AUTHOR=Wang Jing , Liu Sen , Luo Jiahuan , Hou Shaogang , Song Haixiang , Niu Yongsheng , Zhang Chuanxiang 

TITLE=Conductive Metal-Organic Frameworks for Amperometric Sensing of Paracetamol

JOURNAL=Frontiers in Chemistry

VOLUME=8

YEAR=2020

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2020.594093

DOI=10.3389/fchem.2020.594093

ISSN=2296-2646

ABSTRACT=<p>An electrochemical sensor for paracetamol is executed by using conductive MOF (NiCu-CAT), which is synthesized by 2, 3, 6, 7, 10, 11-hexahydroxytriphenylene (HHTP) ligand. The utility of this 2D NiCu-CAT is measured by the detection of paracetamol, p-stacking within the MOF layers is essential to achieve high electrical conductivity, redox activity, and catalytic activity. In particular, NiCu-CAT demonstrated detection Limit of determination near 5μM for paracetamol through a wide concentration range (5–190 μM). The NiCu-CAT/GCE exhibits excellent reproducibility, stability, and interference for paracetamol.</p>