AUTHOR=Fukaya Masashi , Nakamura Seikou , Hayashida Hitoshi , Noguchi Daisuke , Nakashima Souichi , Yoneda Taichi , Matsuda Hisashi 

TITLE=Structures of Cyclic Organosulfur Compounds From Garlic (Allium sativum L.) Leaves

JOURNAL=Frontiers in Chemistry

VOLUME=8

YEAR=2020

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2020.00282

DOI=10.3389/fchem.2020.00282

ISSN=2296-2646

ABSTRACT=<p>Five new cyclic organosulfur compounds, foliogarlic disulfanes A<sub>1</sub> (<bold>1</bold>), A<sub>2</sub> (<bold>2</bold>), and A<sub>3</sub> (<bold>3</bold>) and foliogarlic trisulfane A<sub>1</sub> (<bold>4</bold>) and A<sub>2</sub> (<bold>5</bold>), were isolated from the leaves of <italic>Allium sativum</italic> (garlic). The chemical structures of these compounds were elucidated on the basis of physicochemical evidence including Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS). Compounds <bold>1</bold>–<bold>5</bold> were obtained as complex compounds with disulfane or trisulfane and tetrahydro-2<italic>H</italic>-difuro[3,2-<italic>b</italic>:2′,3′-<italic>c</italic>]furan-5(5a<italic>H</italic>)-one. In addition, the hypothetical biosynthetic pathways of these compounds were suggested.</p>