AUTHOR=Yamada Takeshi , Seto Hideki TITLE=Quasi-Elastic Neutron Scattering Studies on Hydration Water in Phospholipid Membranes JOURNAL=Frontiers in Chemistry VOLUME=8 YEAR=2020 URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2020.00008 DOI=10.3389/fchem.2020.00008 ISSN=2296-2646 ABSTRACT=

The dynamic behavior of hydration water in phospholipid membranes has been investigated to understand the relationship between water and biological molecules using various experimental techniques. Quasi-elastic neutron scattering (QENS) is an effective method for this purpose because the dynamic behaviors of both water and lipid molecules could be identified by using selective deuteration. In addition, the measurable ranges from the 10−12 to 10−9 s time scale and the 10−11 to 10−8 m length scale are suitable to investigate the slowing down of water molecules due to their interaction with lipid membranes. In this mini-review, QENS experiments on the dynamic behavior of hydration water molecules in neighboring phospholipid membranes are summarized.