AUTHOR=Skibińska Monika , Kaźmierczak Marcin , Milcent Thierry , Cytlak Tomasz , Koroniak Henryk , Crousse Benoit 

TITLE=Direct Access to Substituted 4-CF3 β-Lactams at the C-3 Position

JOURNAL=Frontiers in Chemistry

VOLUME=7

YEAR=2019

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2019.00526

DOI=10.3389/fchem.2019.00526

ISSN=2296-2646

ABSTRACT=<p>Mono- and disubstituted 4-CF<sub>3</sub> β-lactams at the C-3 position have been obtained stereoselectively under basic conditions. A wide range of function such as alcohols, alkyls, aryls, esters, and double and triple bonds have been introduced.</p>