AUTHOR=Bruniaux Sophie , Varma Rajender S. , Len Christophe 

TITLE=A Novel Strategy for Selective O-Methylation of Glycerol in Subcritical Methanol

JOURNAL=Frontiers in Chemistry

VOLUME=7

YEAR=2019

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2019.00357

DOI=10.3389/fchem.2019.00357

ISSN=2296-2646

ABSTRACT=<p>A new regioselective approach has been elaborated for the selective conversion of bio-based glycerol into the monomethyl derivative using sub/supercritical methanol. The reaction was realized in a batch process using three reactive components, namely, glycerol, methanol, and potassium carbonate to selectively produce the 3-methoxypropan-1,2-diol in mild yields; the mechanism of the <italic>O</italic>-methylation has been delineated using labeled methanol and GC-MS experiments.</p>