AUTHOR=Malucelli Giulio , Dore Jvan , Sanna Davide , Nuvoli Daniele , Rassu Mariella , Mariani Alberto , Alzari Valeria 

TITLE=Sliding Crosslinked Thermoresponsive Materials: Polypseudorotaxanes Made of Poly(N-Isopropylacrylamide) and Acrylamide-γ-Cyclodextrin

JOURNAL=Frontiers in Chemistry

VOLUME=6

YEAR=2018

URL=https://www.frontiersin.org/journals/chemistry/articles/10.3389/fchem.2018.00585

DOI=10.3389/fchem.2018.00585

ISSN=2296-2646

ABSTRACT=<p>Novel polypseudorotaxanes (PPR) based on poly(N-isopropylacrylamide) (PNIPAAm) and acrylamide-γ-cyclodextrin (AγCD) are successfully synthesized. AγCD gives rise to sliding crosslinking systems and influences the thermoresponsive and swelling behavior of PNIPAAm hydrogels. Namely, their lower critical solution temperature (LCST) can be tuned up to 38°C, thus making the resulting materials of great interest in biomedical applications. Also, AγCD influences the thermal and mechanical properties of hydrogels, by affecting the <italic>T</italic><sub>g</sub> and <italic>E</italic> modulus values.</p>